ALK signaling and target therapy in anaplastic large cell lymphoma
The discovery Kitchen by Morris SW et al.in 1994 of the genes contributing to the t(2;5)(p23;q35) translocation has put the foundation for a molecular based recognition of Anaplastic Large Cell Lymphoma (ALCL) and pointed out the need for a further stratification of T-cell neoplasia.Likewise the detection of ALK genetic lesions among many human can